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Caroline Rauffenbart on Muck Rack

Caroline Rauffenbart

As seen in: ACS Publications, Science Magazine
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Articles

Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning

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By Rui Yang, Ying Yuan, Amaia Ochandorena-Saa, Joy Adler, Ying Zhu, Charlize Szeto, Lisa Lin, Caroline Rauffenbart, Arturo Torres-Herraez, Wesley Asher, Jonathan A. Javitch, Christopher Ford
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Dopamine D2 receptors (D2Rs) modulate reward learning and aversive behaviors, with dysfunction linked to addiction and psychiatric disorders.
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Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D2 Receptor

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By Herman D. Lim, Damian Bartuzi, Alastair C. Keen, Caroline Rauffenbart
| ACS Publications
Introduction Click to copy section linkSection link copied! Monoamine dopamine (DA) acts via G protein-coupled dopamine receptors to modulate physiological processes including motor function, reward mechanisms, and the learning process. (1) This family of five receptors (D1–5R) is divided into the Golf/s -coupled D1-like receptors (D1R and D5R) and the D2-like (D2R, D3R, and D4R) that couple to the Gαi/o/z family of G proteins to inhibit cAMP production.
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