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Damu Sunil Kumar on Muck Rack

Damu Sunil Kumar

As seen in: BioRxiv
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Articles

Nucleolin acute degradation reveals novel functions in cell cycle progression and division in TNBC

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By Joseph Mills, Anna Tessari, Vollter Anastas, Damu Sunil Kumar
| BioRxiv
Abstract Nucleoli are large nuclear sub-compartments where vital processes, such as ribosome assembly, take place. Technical obstacles still limit our understanding of the biological functions of nucleolar proteins in cell homeostasis and cancer pathogenesis. Since most nucleolar proteins are essential, their abrogation cannot be achieved through conventional approaches. Additionally, the biological activities of many nucleolar proteins are connected to their physiological concentration.
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