Dan Tang
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Articles by Dan Tang
CELF2 promotes 4R Tau splicing via nuclear clustering and drives cognitive dysfunction in tauopathy models
Abstract Alternative splicing is a fundamental mechanism underlying protein diversity. The microtubule-associated protein tau (MAPT) undergoes age-associated alternative splicing of exon 10 to generate 3 R and 4 R isoforms, and disruption of the 4 R:3 R ratio is a central feature of tauopathies. However, the molecular mechanisms regulating tau exon 10 splicing remain incompletely understood.
Design, Synthesis, and Biological Evaluation of a MyD88-Targeted Molecular Glue d21 for the Treatment of Acute Lung Injury Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleJune 12, 2026 Design, Synthesis, and Biological Evaluation of a MyD88-Targeted Molecular Glue d21 for the Treatment of Acute Lung Injury Click to copy article linkArticle link copied! Luxiao Zhu Luxiao Zhu Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325024, China Dan Tang Dan Tang Chemical Biology Research Center,...
Digital transformation and ESG practices in SMEs: a pathway to entrepreneurial resilience and sustainable growth in emerging economies
Abstract Digital transformation and ESG (environmental, social, and governance) practices are essential forces driving entrepreneurial resilience (ER). However, little has been done to investigate their combined effect, especially about SMEs (small- and medium-sized enterprises) in emerging economies. This study investigates how digital transformation influences ER, paying particular attention to the mediating and moderating roles of ESG practices.
High-Performance Linear Polarization-Sensitive WSe 2 /SnS 0.25 Se 0.75 Heterojunction Photodetectors: Synergy of Type-II Band Alignment and Gate-Modulated Anisotropic Transport Click to copy article link Article link copied!
Functional Inorganic Materials and DevicesApril 28, 2026 Dan Tang Guangdong Provincial Key Laboratory of Chip and Integration Technology, School of Electronic Science and Engineering (School of Microelectronics), Faculty of Engineering, South China Normal University, Foshan 528200, P. R.
Frontiers | Artificial intelligence-driven approaches in pituitary neuroendocrine tumors: integrating endocrine-metabolic profiling for enhanced diagnostics and therapeutics
1 Introduction Pituitary neuroendocrine tumors (PitNETs) are the second most common intracranial tumors, comprising approximately 15% of all intracranial neoplasms and representing the most prevalent neuroendocrine tumors in adults, with an estimated annual incidence of 3.9 per 100,000 individuals (1). These tumors exhibit diverse biological behaviors, including variable growth patterns and invasive potential.
Zn‐Catalyzed Cycloisomerization/Methylenation of Enyone with Vinyl Azide: Assembly of Terminal and Deuterated Alkenyl Furan Framework
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Distributionally Robust Energy Optimization with Renewable Resource Uncertainty
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study
eLife Assessment This useful study examined the associations of a healthy lifestyle with comprehensive and organ-specific biological ages defined using common blood biomarkers and body measures. Its large sample size, longitudinal design, and robust statistical analysis provide solid support for the findings, which will be of interest to epidemiologists and clinicians.
Intelligent Recommendation of Multi-Scale Response Strategies for Land Drought Events
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Pharmacokinetics, relative bioavailability, and safety of the SHR0302 | DDDT
Introduction Graft-versus-host disease (GVHD) is a clinicopathological syndrome caused by donor-derived lymphocytes attacking the recipient’s organs during the immune reconstitution phase following allogeneic hematopoietic stem cell transplantation (allo-HSCT). It is the most common complication and a leading cause of death in allo-HSCT.
Research on Named Entity Recognition Based on Gated Interaction Mechanisms
1. Introduction Named entity recognition (NER) [1] has been a popular research field. NER technology has evolved from initially relying on rules and dictionaries to traditional machine learning models and then to various deep learning techniques [2].
Adsorption Capability and Mechanism of Pb(II) Using MgO Nanomaterials Synthesized by Ultrasonic Electrodeposition
1. Introduction Lead (Pb)-contaminated soils contain high levels of Pb due to excessive industrial activity; this causes the metal to continuously release into the soil. Pb-contaminated soils contain various substances, including elevated heavy metal concentrations including arsenic, mercury, and chromium, as well as organic contaminants, organic matter, and soil minerals [1,2,3].
Reviewing CAM-Based Deep Explainable Methods in Healthcare
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Rapid and green quantification of phloridzin and trilobatin in Lithocarpus litseifolius (Hance) Chun (sweet tea) using an online pressurized liquid extraction high-performance liquid chromatography at equal absorption wavelength method
Rapid and green quantification of phloridzin and trilobatin in Lithocarpus litseifolius (Hance) Chun (sweet tea) using an online pressurized liquid extraction high-performance liquid chromatography at equal absorption wavelength method† Sweet tea is a functional herbal tea with anti-inflammatory, anti-diabetic, and other effects, in which phloridzin and trilobatin are two functional compounds.
Magnesium Magic: State‐of‐the‐Art Nanocrystalline Materials Paving the Way for Hydrogen Storage
Hydrogen has been regarded as a promising alternative to traditional fossil fuels, presenting itself as a viable and environmentally friendly energy choice. The design and fabrication of highly efficient hydrogen storage materials is crucial to the wide utilization of hydrogen-based technologies. Magnesium-based nanocrystalline materials have received significant interest in the field of hydrogen storage due to their remarkable hydrogen storage capabilities and release efficiency.
Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations
Supporting Information Filename Description jhet4791-sup-0001-supinfo.docxWord 2007 document , 4.2 MB Data S1. Supporting information. REFERENCES 1, , , , , , , CA-Cancer J. Clin. 2021, 71, 209. 2, , , , , , , , , , , , , , , , S. Collaborators, Lancet Oncol. 2023, 24, 22. 3, , , J. Med. Chem. 2014, 57, 5845. 4, , , , , Eur. J. Med. Chem. 2015, 102, 552. 5, Nat. Prod. Rep. 2007, 24, 223. 6, , , , , , , , , J. Heterocyclic Chem. 2022, 59, 1086. 7, , , , , , , J. Heterocyclic Chem. 2022, 59, 555. 8, , , , , , , Chem.
Advances in the Study of the Pathology and Treatment of Alzheimer’s Disease and Its Association with Periodontitis
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Engineered dsRNA-protein nanoparticles for effective long-distance transport, delivery and gene silencing in plants
Abstract Long-distance transport of exogenous biologically active RNA molecules in higher plants has not been reported. Here, we report that cationized bovine serum albumin (cBSA) avidly binds double-stranded beta-glucuronidase RNA (dsGUS RNA) to form nucleic acid-protein nanocomplexes.
Transcriptome Reveals the Mechanism of Immunity in the Low Salinity Stress of the Chinese Shrimp (Fenneropenaeus chinensis)
Dan Tang [1] ; Ya Wu [1] ; Suping Huang [1] ; Lv Wu [1] ; Yaqi Luo [1] ; Zhengfei Wang [1] [1] Yancheng Teachers University Localización: Thalassas: An international journal of marine sciences, ISSN 0212-5919, Vol. 38, Nº. 2 (October 2022), 2022, págs. 977-987 Idioma: inglés Enlaces Texto completo The Chinese shrimp (Fenneropenaeus chinensis) is mainly economically important cultured species in the aquaculture of China, and it has a strong adaptability to changes in salinity (18ppt-32ppt).
Whose migration matters? The role of migration in social networks and mental health among rural older adults in China | Ageing & Society | Cambridge Core
Hostname: page-component-69598c5f4d-zfbz9 Total loading time: 0 Render date: 2023-05-15T03:33:11.925Z Has data issue: false Feature Flags: { "useRatesEcommerce": false } hasContentIssue false Published online by Cambridge University Press: 17 August 2021 Show author details Abstract The dual demographic changes in massive rural-to-urban labour migration and population ageing have significantly impacted the lives of older adults, who have either been left behind in rural regions or migrated to...
Efficacy of traditional Chinese medicine injection for diabetic kidney disease: A network meta analysis and systematic review
Caiyi Long1,2†, Haoyue Feng1,2†, Zheng Liu1,2, Zihan Li1,2, Jun Liu3, Yayi Jiang1,2 and Rensong Yue1* 1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China 2Chengdu University of Traditional Chinese Medicine, Chengdu, China 3People’s Hospital of Nanjiang County, Bazhong, China Background: Diabetic kidney disease (DKD) is an important public health problem worldwide that increases the mortality of patients and incurs high medical costs.
Effect of Lidar Receiver Field of View on UAV Detection
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Zijian Chen 1,2, Yu Miao 3,*, Dan Tang 1, Hao Yang 1 and Wenwu Pan 1 1 Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900, China 2 Graduate School, China Academy of Engineering Physics, Beijing 100088, China 3 State Key Laboratory of Pulsed Power Laser Technology, Changsha 410073, China * Author to whom correspondence should be addressed.
Study of Lovastatin and L-Arginine Co-loaded PLGA Nanomedicine for Enhancing Nitric Oxide Production and eNOS Expression
Study of Lovastatin and L-Arginine Co-loaded PLGA Nanomedicine for Enhancing Nitric Oxide Production and eNOS Expression Nitric oxide (NO) is an exceptional endogenous biological molecule gas that mediates and regulates physiological and pathological processes in the human body. However, its synthesis process is impaired during athero-progression and formation.
Separated kin: location of multiple children and mental health trajectories of older parents in rural China
Abstract Objective This study examines the longitudinal association between the location of multiple children and depressive symptoms of older parents in rural China, where massive rural-to-urban migration has profoundly altered the family life of the aging population.
Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a
Cryo-EM structure of C9ORF72–SMCR8–WDR41 reveals the role as a GAP for Rab8a and Rab11a Dan Tang, Jingwen Sheng, Liangting Xu, Xiechao Zhan, Jiaming Liu, Hui Jiang, Xiaoling Shu, Xiaoyu Liu, Tizhong Zhang, Lan Jiang, Cuiyan Zhou, Wenqi Li, Wei Cheng, Zhonghan Li, Kunjie Wang, Kefeng Lu, Chuangye Yan, Shiqian Qi Proceedings of the National Academy of Sciences Apr 2020, 202002110; DOI: 10.1073/pnas.2002110117
ACC1 (Acetyl Coenzyme A Carboxylase 1) Is a Potential Immune Modulatory Target of Cerebral Ischemic Stroke
Peiying Li Correspondence to Peiying Li, MD, PhD, Department of Anesthesiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Rd, Rm 117, Bldg 11, Shanghai, 200127, People’s Republic of China, Email E-mail Address: [email protected] From the Department of Anesthesiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, China (X.W., Y.Z., D.T., Z.Z, Y.L., T.H., P.L., W.Y.)
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