Daniel Almeida Filho

Abstract Events occurring close in time are often linked in memory, and recent studies suggest that such memories are encoded by overlapping neuronal ensembles. However, the role of dendritic plasticity mechanisms in linking memories is unknown. Here we show that memory linking is dependent not only on neuronal ensemble overlap in the mouse retrosplenial cortex, but also on branch-specific dendritic allocation mechanisms.

Achterberg E.J. van Kerkhof L.W. Servadio M. van Swieten M.M. Houwing D.J. Aalderink M. Driel N.V. Trezza V. Vanderschuren L.J. Contrasting roles of dopamine and noradrenaline in the motivational properties of social play behavior in rats. Neuropsychopharmacology. 2016; 41: 858-868https://doi.org/10.1038/npp.2015.212 Circuit investigations With open-source miniaturized microscopes: past, present and future. Front. Cell. Neurosci. 2019; 13: 141https://doi.org/10.3389/fncel.2019.00141 Aharoni D.

Abstract Real-world memories are formed in a particular context and are often not acquired or recalled in isolation1,2,3,4,5. Time is a key variable in the organization of memories, as events that are experienced close in time are more likely to be meaningfully associated, whereas those that are experienced with a longer interval are not1,2,3,4. How the brain segregates events that are temporally distinct is unclear.