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Daniel Bar

As seen in: Nature, The BMJ, The Toronto Star, Todo Noticias, BioRxiv, Embedded Computing Design
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Articles

Antiphospholipid syndrome in the paediatric population: performance of ACR-EULAR classification criteria in a controlled cohort

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By Stanley Niznik, Daniel Bar, Shiri Spielman
| The BMJ Verified
Limited data regarding classification criteria in the paediatric population, specifically in the era of newer American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR-EULAR) antiphospholipid syndrome (APS) classification criteria.
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Decoding regional keratinization in human oral mucosa through high-resolution spatial transcriptomics

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By Michal Lusthaus, Ana J Caetano, Rami Khosravi, Carlos Nemcovsky, Daniel Bar, Evgeny Weinberg, Noy Rosental Vazani, Avital Sarusi Portuguez, Miron Weinreb
| Nature Verified
Abstract Oral mucosa exhibits region-specific keratinization, essential for periodontal health, yet the spatial and molecular mechanisms driving these differences remain poorly understood. This study aimed to generate a high-resolution spatial transcriptomic atlas of the human oral mucosa around the mucogingival junction, to reveal stromal-epithelial interactions, that distinguish keratinized from non-keratinized programs.
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SIRT6 overexpression counteracts chromatin aging in the male murine liver

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By Ron Nagar, Zacharia Schwartz, Almog Katz, Noga Touitou, Efrat Sharon, Kobi Tzdaka, Odeya Waner, Noam Shalev, Rotem Clo, Leah Weiss, Benjamin Epstein, Michel Bernier, Roni B Shtark, Nirad Banskota, Kwan-Wood G. Lam, Supriyo De, Nathan Price, Batia Lerrer, Daniel Bar, Rafael de Cabo, Haim Cohen
| Nature Verified
Abstract Aging is associated with detrimental changes in chromatin structure and gene expression, contributing to inflammation, metabolic decline and tissue dysfunction. SIRT6, a histone deacetylase, plays a key role in maintaining chromatin integrity and promoting longevity.
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