Updated Mon, June 8, 2026 at 10:31 AM UTC How an experimental weight-loss drug is being openly promoted by physicians Retatrutide isn't supposed to be everywhere. Touted as the next generation in the GLP-1 craze, it's an experimental weight-loss drug that is not authorized outside of clinical trials. The Food and Drug Administration hasn't reviewed whether it is safe and effective, which is the legal path for prescription drugs to come to market.