Daniel J. DeAngelo, MD, PhD, physician and chief of the Division of Leukemia at Dana-Farber Cancer Institute and professor of medicine at Harvard Medical School, discussed the evolving treatment strategies in acute lymphoblastic leukemia (ALL) management, particularly for patients with Philadelphia chromosome (Ph)–positive disease, which were discussed during the 2026 Bridging the Gaps in Leukemia, Lymphoma, and Multiple Myeloma Conference.