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Xiang Yin

As seen in: Color Research & Application, Nature, Wiley Online Library, arXiv, ScienceDirect, Frontiers, MDPI, ACS Publications, Royal Society of Chemistry, Cell Reports and
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Articles

Comparison of obecabtagene autoleucel versus an external control arm in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia

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By Max S. Topp, Bijal Shah, Elias Jabbour, Jae Park, Paul W. Shaughnessy, Aaron Logan, Karamjeet S. Sandhu, Mehrdad Abedi, Michael Bishop, Daniel DeAngelo, Xiang Yin, Ruthanna Davi, Katharine A. Hodby, Ram Malladi, Wolfram Brugger, Claire Roddie, Hagop Kantarjian, Justin Shang
| Nature Verified
Abstract In the single-arm Phase Ib/II FELIX study (NCT04404660), obecabtagene autoleucel (obe-cel; CD19-directed autologous CAR T-cell therapy) demonstrated high overall remission rates (ORR) and a favorable safety profile in adults with relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). To contextualize results from FELIX, we compared the efficacy and safety of obe-cel with matched external control arms (ECA) derived from historical trials using propensity score matching.
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TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence

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By Jiamin Huang, Yayu Wang, Yudong Xu, Yanan Wei, Xiang Yin, Junling Li, Yu Zeng, Meiting Chen, Canjun Li, Li Wang, Xiaomei Li, Lili Qu, Chunlei Cang
| Cell Reports Verified
ArticleVolume 45, Issue 7117703Open access Affiliations & Notes 1Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, State Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230027, China 2Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Neurodegenerative Disorder Research Center, University of Science and Technology of China,...
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Room-Temperature 2D Topological Ferrimagnetic Semiconductors With Multiple Electronic Phase Transitions

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By Li Deng, Fei Wang, Xiang Yin
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm77152-sup-0001-SuppMat.pdf34.7 MB Supporting File: adfm77152-sup-0001-SuppMat.pdf. References 1, “Antiferromagnetism and Ferrimagnetism,” Proceedings of the Physical Society Section A 65 (1952): 869–885.
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