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Daniel J Kyabayinze

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Emergence of a Bundibugyo virus variant in the 2026 outbreak in the Democratic Republic of the Congo and Uganda

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By Adrienne Amuri-Aziza, Gradi Luakanda-Ndelemo, Alisen Ayitewala, Daan Jansen, Eddy Kinganda-Lusamaki, Stephen Kanyerezi, Pontiano Kaleebu, Christian B. Ngandu, Allan N. Muruta, Daudi Jjingo, Susan Nabadda, Raphael Lumembe-Numbi, Misaki Wayengera, John O. Otshudiema, Judith Kyokushaba, Daniel J Kyabayinze, Uganda Ministry, Henry Kyobe Bosa, Daniel Mukadi-Bamuleka, Charles Olaro, Ahidjo Ayouba, Sabue Mulangu, Aloysious Ssemaganda, Nick Loman, Anne W. Rimoin, Samuel W. Wilkinson, Kevin K Ariën, Steve Ahuka-Mundeke, Áine O’Toole, Dieudonné K. Mwamba, Christian T. Happi, Martine Peeters, Laurens Liesenborghs, Piet Maes, Miles W Carroll, Jason Kindrachuk, Pierre Akilimali, Andrew Rambaut, Koen Vercauteren, Tony Wawina-Bokalanga, Isaac Ssewanyana, Placide Mbala-Kingebeni, Pascal Adroba-Tandele, Andrew Tebba, Olga Ntumba-Tshitenge, Ibrahimm Mugerwa, ACE-Uganda consortium, Princesse Paku-Tshambu, Atek Kagiria, Benard Lubwama
| Nature Verified
Abstract In May 2026, an outbreak of Ebola disease caused by Bundibugyo virus (BDBV, species Orthoebolavirus bundibugyoense) was declared in the Democratic Republic of the Congo (DRC), with cases originating from DRC and locally transmitted cases reported in Uganda. Bundibugyo virus disease (BVD) outbreaks were previously recorded in 2007-2008 in Bundibugyo District, Uganda, and in 2012 in Isiro, DRC. Here, we generated 22 genomes from samples obtained from individuals with BVD in DRC and Uganda.
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