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Ronnie Bahatungire

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Articles

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak

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By Gradi Luakanda-Ndelemo, Alisen Ayitewala, Pascal Adroba-Tandele, Andrew Walakira, Adrienne Amuri-Aziza, Daan Jansen, Ronald Galiwango, Eddy Kinganda-Lusamaki, Andrew Tebba, Christian B. Ngandu, Aloysious Ssemaganda, Olivier Tshiani-Mbaya, Stephen Kanyerezi, Judith Kyokushaba, Hellen Rosette Oundo, Servet Kimbonza, Stephen Balinandi, Daniel Mukadi-Bamuleka, Valeria Nakintu, Justus Nsio, Ibrahimm Mugerwa, Daniel Kadobera, Sabue Mulangu, Ahidjo Ayouba, Henry Kyobe Bosa, Misaki Wayengera, Anne W. Rimoin, Benard Lubwama, Atek Kagirita, Steve Ahuka-Mundeke, Dieudonné K. Mwamba, Andrew Kambugu, Pontiano Kaleebu, Christian T. Happi, Laurens Liesenborghs, Miles W Carroll, Piet Maes, Jean B. Nachega, Martine Peeters, Pierre Akilimali, Allan N. Muruta, Jason Kindrachuk, Andrew Rambaut, Daniel J Kyabayinze, Charles Olaro, Koen Vercauteren, Susan Nabadda, Diana Atwine, Daudi Jjingo, Tony Wawina-Bokalanga, Placide Mbala-Kingebeni, Isaac Ssewanyana, Kevin Cissy Nabukeera, Syrus Semawule, Carol Makoha, Daniel Euriene, Micheal Eliu, Sam Gidudu, Ronnie Bahatungire
| Nature Verified
Abstract The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, including 12 from the 2026 outbreak, to assess mAb binding to the viral glycoprotein (GP).
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