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Articles by Daniel Stow
Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink
Loading metrics Open Access Peer-reviewed Research Article Citation: Eto F, Samuel M, Stow D, Henkin R, Angdembe A, Barnes MR, et al. (2026) Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink. PLoS Med 23(8): e1005196.
Genetic and sociodemographic factors associated with trajectories of physical and mental health multimorbidity in a South Asian cohort in the UK: A multistate modelling analysis
Loading metrics Open Access Peer-reviewed Research Article Citation: Stow D, Tsang RSM, Katzourou IK, Huang Q, Samuel M, Wood ML, et al. (2026) Genetic and sociodemographic factors associated with trajectories of physical and mental health multimorbidity in a South Asian cohort in the UK: A multistate modelling analysis. PLoS Med 23(7): e1004844.
Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores
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Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores Supplement 1. eFigure 1. Associated Odds Ratios and Confidence Intervals Resulted From the Sensitivity Analysis for Grouping rCNVs Across 6 Different Approaches eFigure 2. Comparison of rCNV Group-Associated Absolute Risk Between SSD and SSD Without Comorbid Childhood-Onset Disorders in iPSYCH2015 eFigure 3.
By Morteza Vaez, Simone Montalbano, Ryan K. Waples, Morten Krebs, Kajsa-Lotta Georgii Hellberg, Jesper R. Gådin, Daniel Stow, Peter A Holmans, Anders D. Børglum, Dorte Helenius, Thomas Werge, Andrew J. Schork, Andrés Ingason, LINC Consortium, George G. Kirov, Michael Owen, James Walters, Jane Lynch, David van Heel, Sarah Finer, Nicholas J Timpson, John MacLeod Verified, Julie Clayton, Ruby Tsang, Jane Sprackman, Shahid Khan, Inês Barroso, Rupert A Payne, Mark A. Mon-Williams, Megan Wood, Nabila Ali, Hilary C. Martin, Lam O. Huang, Marianne van den Bree, Ioanna K. Katzourou, Golam M. Khandakar
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JAMA Psychiatry
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Immunometabolic blood biomarkers of developmental trajectories of depressive symptoms: findings from the ALSPAC birth cohort - Molecular Psychiatry
The lived experiences of people dying with frailty: a systematic review and thematic synthesis of qualitative studies exploring patients, relatives and professionals views
The authors have declared no competing interest. DS and BKB were supported by NIHR School For Primary Care Research launching fellowships, EW was supported by Newcastle University institutional funding, BH is funded by the Applied Research Collaboration. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Genetic architecture of routinely acquired blood tests in a British South Asian cohort - Nature Communications
Abstract Understanding the genetic basis of routinely-acquired blood tests can provide insights into several aspects of human physiology. We report a genome-wide association study of 42 quantitative blood test traits defined using Electronic Healthcare Records (EHRs) of ~50,000 British Bangladeshi and British Pakistani adults. We demonstrate a causal variant within the PIEZO1 locus which was associated with alterations in red cell traits and glycated haemoglobin.
Immunometabolic Blood Biomarkers of Developmental Trajectories of Depressive Symptoms: Findings From the ALSPAC Birth Cohort
The authors have declared no competing interest. This work was funded by the Tackling Multimorbidity at Scale Strategic Priorities Fund programme (MR/W014416/1) delivered by the UK Medical Research Council (MRC) and the UK National Institute for Health Research (NIHR) in partnership with the UK Economic and Social Research Council and in collaboration with the UK Engineering and Physical Sciences Research Council. RSMT, DS and MLW are supported by this grant.
Perceived risk of type 2 diabetes: Using linked genomic, clinical and questionnaire data to understand the potential use of genetic risk tools in British South Asians
The authors have declared no competing interest. This work was made possible by funding from the Wellcome Trust for JHL through the doctoral training programme Health Data in Practice: Human-centred Science (Reference: 218584/Z/19/Z).
Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease - Nature Communications
Abstract Thyroid hormones play a critical role in regulation of multiple physiological functions and thyroid dysfunction is associated with substantial morbidity. Here, we use electronic health records to undertake a genome-wide association study of thyroid-stimulating hormone (TSH) levels, with a total sample size of 247,107.
Which interventions are effective at decreasing or increasing emergency department attendances or hospital admissions from long-term care facilities? A systematic review
Methods Search strategy and selection criteria We searched for randomised controlled trials with people living in long-term care facilities (the population), interventions delivered in primary care or the long-term care facility, that intended to influence acute hospital admissions or ED attendances (the outcome). Studies involving people living in private households, warden-controlled homes, supported living facilities or living at home with carers were excluded.
Which Interventions are Effective at Decreasing or Increasing Hospital Attendances or Hospital Admissions from Care Homes?
Abstract Which interventions are effective at decreasing or increasing hospital attendances or hospital admissions from care homes? A systematic review Context: Care home residents in the UK care homes account for almost 1.5 million emergency bed days each year. Avoidance of unnecessary hospital transfers benefits residents, and reduces demand on the healthcare systems but is difficult to implement.
Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use
Background Socioeconomic status is a construct that reflects a person’s economic circumstances and their social capital relative to that of others.1 The concept is central to understanding health inequalities,2 3 where a gradient describes differences in health outcomes between the least and most advantaged.4 Both socioeconomic status and position are used in the health inequalities literature.
Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use
Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use http://orcid.org/0000-0003-2121-4529Gemma Frances Spiers1, Jennifer E Liddle1, http://orcid.org/0000-0002-9534-4521Daniel Stow2, Ben Searle1, Ishbel Orla Whitehead1, Andrew Kingston1, Suzanne Moffatt1, Fiona E Matthews1, http://orcid.org/0000-0002-3122-7190Barbara Hanratty1 1Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK 2Population...
Does moderate alcohol consumption accelerate the progression of liver disease in NAFLD? A systematic review and narrative synthesis
Characteristics of included studies Further details of included studies are shown in table 2. View this table: Within the studies meeting inclusion criteria, three58–60 looked at the exposure of alcohol consumption up to, or similar to, the accepted international definition of moderate consumption.
Can vaccination roll-out be more equitable if population risk is taken into account?
Loading metrics Open Access Peer-reviewed Research Article David R. Sinclair , Asri Maharani, Daniel Stow, Claire E. Welsh, Fiona E. Matthews David R. Sinclair, Asri Maharani, Daniel Stow, Claire E. Welsh, Fiona E. Matthews Published: November 15, 2021 https://doi.org/10.1371/journal.pone.0259990 Figures Abstract Background COVID-19 vaccination in many countries, including England, has been prioritised primarily by age. However, people of the same age can have very different health statuses.
Timing of GP end-of-life recognition in people aged ≥75 years: retrospective cohort study using data from primary healthcare records in England
Research Daniel Stow, Fiona E Matthews and Barbara Hanratty British Journal of General Practice 2020; 70 (701): e874-e879. DOI: https://doi.org/10.3399/bjgp20X713417 Abstract Background High-quality, personalised palliative care should be available to all, but timely recognition of end of life may be a barrier to end-of-life care for older people.
Timing of GP end-of-life recognition in people aged ≥75 years: retrospective cohort study using data from primary healthcare records in England
Research Daniel Stow, Fiona E Matthews and Barbara Hanratty British Journal of General Practice 2 November 2020; bjgp20X713417. DOI: https://doi.org/10.3399/bjgp20X713417 Abstract Background High-quality, personalised palliative care should be available to all, but timely recognition of end of life may be a barrier to end-of-life care for older people.
What is the evidence that people with frailty have needs for palliative care at the end of life? A systematic review and narrative synthesis
What is already known about the topic? Frailty is common among older adults and is associated with an increased risk of dying. Frailty has been proposed as an indicator of need for palliative care. There is a need to review and collate information on the end-of-life care needs of people with frailty. What this paper adds? This study reports that people with frailty have a range of specific physical and psychosocial care needs at the end of life.
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