Danzhi Ying

Cite Jump to ExpandCollapse ArticleOctober 22, 2025 Divergent Synthesis of Alkenyl Sulfur Ylides and Sulfides through Base-Controlled Cascade Reactions of Prop-2-ynylsulfonium Salts and α,α-Dicyanoalkenes Click to copy article linkArticle link copied! Danzhi Ying Danzhi Ying College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China Luyi Zhan Luyi Zhan College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China Jinhua Institute of Zhejiang University,...

In 1908, the synthesis of pyrazolo[3,4-b]pyridines was achieved through a reaction involving diphenylhydrazone, pyridine, and iodine [1]. These compounds possess a molecular structure comprising fused pyridine and pyrazole scaffolds, categorizing them as bicyclic heterocyclic compounds. Due to their nitrogen-rich nature and ability to interact with biomolecules, these derivatives have proven to be effective drugs against various cancerous cells [2], [3].