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Dapeng Yin on Muck Rack

Dapeng Yin

As seen in: Nature, MDPI
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Articles

PRICE: direct and robust detection of microRNAs at single-nucleotide resolution - Nature Communications

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By Buhua Wang, Shuai Zhou, Xi Zhang, Rui Wang, Shuo Huang, Anyi Li, Haowei He, Yangdao Wei, Zhiqing Yang, Fengge Song, Xiangpeng Li, Xinyi Wan, Yi Shen, Chunxin Ma, Rodrigo Ledesma-Amaro, Dapeng Yin, Qingshan Wei, Ruijie deng, Tao Yang, Shanrong Liu, Yi Wan, Chuanbin Mao, Yingai Zhang, Haimei Mao
| Nature Verified
Abstract Accurate single-nucleotide discrimination of miRNA is clinically vital because small sequence variations can have significant phenotypic and clinical consequences, yet existing techniques can only detect single nucleotide variations (SNVs) at specific loci. Here, we present a generalized peptide nucleic acid (PNA) mediated CRISPR/Cas13a system (PRICE), enabling detection of SNVs in miRNA sequence without sacrificing the sensitivity.
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Numerical Study of Cavitation Characteristics through Butterfly Valve under Different Regulation Conditions

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By Guang J Zhang, Dapeng Yin, Desheng Chen, Runhua Hu
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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