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David Barda

As seen in: Nature, Lawyers Weekly
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Articles

Characterization of KRAS G12C inhibitor olomorasib single-agent and combination with activity in KRAS G12C -mutant models

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By Xi Lin, Robert Van Horn, Jack Dempsey, Eva M. Goetz, Robert Evans, Andrew Farber, Matthew J. VandeKopple, Hong Gao, Wei Xu, Nicholas Brown, Michele Dowless, Nicholas Pulliam, David Barda, Serge Boulet, Andrew Capen, Mark A. Castanares, Jennifer Stephens, Megan Johnson Verified, Junpeng Xiao, Josh Ballard, Michael Chalmers, Jing L. Wang, Jörg Hendle, Anita Sarkar, Frances Tung, Joseph Ho, Logan Rodgers, Jordi Obach Benach, Lian Zhou, Bradley L Ackermann, Sean Buchanan, James Henry, Xueqian Gong, Shengbin Peng, Youyan Zhang, Chong Si, Wenyu Ming, Chungping Yu, Deqi Guo, Lysian Huber, Bonita Jones, Sarah Bogner, Carmen L. Curtis, John M. Strelow, Wayne P. Bocchinfuso, Melbert D. Saflor, Danalyn Manglicmot Lagutan, Tarun Gheyi, Margaret Kearins, Anton Joseph Frommelt, Denis McCann, Anke Klippel
| Nature Verified
Abstract The impact of first-generation covalent KRASG12C inhibitors has been reduced due to the development of drug resistance, tolerability and challenges combining with immunotherapy. We designed olomorasib, a next-generation GDP-binding KRASG12C inhibitor, for nanomolar potency as well as selectivity over wild-type inhibition.
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UK Supreme Court shows us that democracy is so much more than just voting

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By Jerome Doraisamy Verified, David Barda
| Lawyers Weekly
Opinion | 30 September 2019 | David Barda Opinion | 30 September 2019 By: David Barda — 3 minute read The Supreme Court of the United Kingdom this week ruled that Boris Johnson’s suspension (or “prorogation”) of parliament was unlawful. In doing so, it dived headfirst into a political thicket, writes David Barda.
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Your digital legacy and protecting virtual assets

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By David Barda
| slatergordon.com.au
If you’re an active internet user you’ve probably heard of the term ‘digital legacy’ or ‘virtual property’ before. You may have even wondered what happens to all of your online accounts if you pass away. And if you’re reading this blog, it means you’re part of the 65% of Australian internet users who are engaged some form of social media.
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