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Life | Free Full-Text | Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics | HTML
Open AccessArticle by Conceição A. Minetti 1,*,†, David P. Remeta 1,*,†, Keiji Hashimoto 2, Radha Bonala 2, Rajesh Chennamshetti 2, Xingyu Yin 2, Miguel Garcia-Diaz 2, Arthur P. Grollman 2,3, Francis Johnson 2,4,* and Viktoriya S.
Magnesium Activates Microsecond Dynamics to Regulate Integrin-Collagen Recognition
Minor Mg-Bound α1I Species Adopts a Unique Conformation that Differs from the α1I Closed and Open States Probing Residues in the α1I Minor Species Population via Mutagenesis and Adhesion Assays L318A Gain-of-Function Mutation Mimics Structural Changes of the Minor Species Allostery in α1I Is Facilitated by the Presence of an Active Intermediate The 15N ZZ-exchange experiments were recorded on a Bruker 700 MHz spectrometer at 20°C using the approach developed by Tollinger’s group (Kloiber et...
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