David Skuse on Muck Rack

David Skuse

United Kingdom
As seen in: BJPsych International Magazine, Color Research & Application, Nature, Autism (The International Journal of Research and Practice), MDPI, Spectrum
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Articles

The influence of genetic factors on education health and care plan obtainment for pupils with intellectual developmental disabilities - Scientific Reports

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By Irene Lee, Jeanne Wolstencroft, Harriet Housby, Jeremy Hall, Michael Owen, David Skuse
| Nature Verified
Abstract The study aimed to investigate the hypothesis that the Education, Health and Care Plan (EHCP) obtainment for pupils with intellectual developmental disabilities (IDD) of genetic aetiology was influenced by genetic factors and their family’s socioeconomic status. We recruited 2738 participants with IDD of genetic aetiology aged between 6–28 years old (mean age 14 years, 56% male).
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Irritability in young people with copy number variants associated with neurodevelopmental disorders (ND-CNVs) - Translational Psychiatry

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By Jessica Hall, David Skuse, Jeremy Hall, Peter A Holmans, Michael Owen
| Nature Verified
Abstract A range of rare mutations involving micro-deletion or -duplication of genetic material (copy number variants (CNVs)) have been associated with high neurodevelopmental and psychiatric risk (ND-CNVs). Irritability is frequently observed in childhood neurodevelopmental conditions, yet its aetiology is largely unknown.
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Early-Onset Psychosis and Autism Spectrum Disorder: Similar Rates of Deleterious Copy Number Variants, Yet Diverse Phenotypic Manifestations

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By David Skuse
There is long-standing evidence that in adults a genetic overlap exists in risk between autism spectrum disorder (ASD), schizophrenia, and intellectual disability (1, 2). A range of recurrent copy number variants (CNVs) in specific loci, and to some extent single-nucleotide variants (SNVs) (3), appear to be responsible.
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