Skip To Main Content
David Leigh on Muck Rack

David Leigh

London
As seen in: Arthritis & Rheumatology, Color Research & Application, Daily Mail, El País, Nature, The Daily Mirror, The Guardian, Wiley Online Library, ACS Publications, American Chemical Society and
Author of "Investigative Journalism: a survival guide" ( Palgrave) bit.ly/2lLQhSy. ex-Guardian Investigations Editor. Appalled by Musk, gone to Bluesky
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with David

Contact David, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Trefoil polymers from a knotted synthon

|
By Chenchen Du, Zhi Chen, Changqing Xu, Zhanhu Sun, Zhi-Hui Zhang, Binhua Chen, Chenxin Zhang, Zhikai Li, Yin Rao, Deao Xu, Ningjin Zhang, Qiaowei Li, Heng Wang, Hai Qian, Liang Dai, Xiaopeng Li, David Leigh, Liang Zhang, Xian-Guang Liu
| Nature Verified
Abstract Precise control over the presence and position of knots in polymers remains a long-standing synthetic challenge, with theory indicating broad implications for properties and function. Here we report on a topological synthon approach—extension and macrocyclization of an overhand knot—that enables the high yielding synthesis of closed-loop trefoiled polymers with narrow polydispersity and tunable topological parameters.
Open in Who Shared Issue with article?

Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization

|
By Jiankang Zhong, Axel Troncossi, Enzo Olivieri, Emily Cramp, Patrick Zwick, George Whitehead, David Leigh
| Nature Verified
Abstract Rotaxane synthesis generally requires the macrocycle to contain recognition sites for the threaded axle or its building blocks. Here we show that flexible oligo(ethylene glycol) axles can instead promote the formation of macrocycles around themselves, enabling an inverted, metal-free active-template route to rotaxanes from simple building blocks. The axle accelerates amide-bond-forming macrocyclization through hydrogen bonding, giving [2]rotaxanes in up to 70% yield.
Open in Who Shared Issue with article?

Justice but too late for Brave Claudia

|
By David Leigh
| The Tribune 242 Verified
By DAVID LEIGH Tribune Editor-in-Chief. daleigh@tribunemedia.net THE highest court of appeal has confirmed the Bahamian government is liable for the unlawful arrest and detention of a young mother who was raped and sexually assaulted by a senior immigration officer while in custody.
Open in Who Shared Issue with article?
See all 105 licensed articles (234 Total)