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Débora Broch Trentini on Muck Rack

Débora Broch Trentini

As seen in: PNAS, BioRxiv
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Articles

Principles of ribosome-associated protein quality control during the synthesis of CFTR

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By Tom Oldfield Verified, Débora Broch Trentini, Robin Renn
| BioRxiv
Abstract Prolonged translational arrests caused by defective mRNAs activate the ribosome-associated protein quality control (RQC) pathway, which marks harmful incomplete proteins for degradation. Multipass transmembrane proteins have increased propensity to be targeted by the RQC, raising the question of whether problems in transmembrane domain insertion and assembly can also cause RQC-eliciting translational arrests.
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Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation

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By Shivani Tiwary, Jürgen Cox, Débora Broch Trentini, Matteo Pecoraro
| PNAS Verified
Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation Débora Broch Trentini, Matteo Pecoraro, Shivani Tiwary, Jürgen Cox, Matthias Mann, Mark S. Hipp, F. Ulrich Hartl Proceedings of the National Academy of Sciences Feb 2020, 201914401; DOI: 10.1073/pnas.1914401117
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