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Defeng Yin on Muck Rack

Defeng Yin

As seen in: Nature
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Articles

Lysosome-related biomarkers in peripheral blood immune cells discriminate sepsis from SIRS

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By Chenglin Wang, Lu Liu, Haili Li, Yingchun Hu, Hao Jiang, Defeng Yin
| Nature Verified
Abstract This study aimed to screen lysosome-related genes that distinguish sepsis from Systemic Inflammatory Response Syndrome (SIRS), in order to provide potential targets for the differential diagnosis of sepsis and for lysosome-targeted therapeutic strategies. Peripheral blood samples were collected from 12 SIRS patients and 20 sepsis patients for RNA sequencing and differential expression analysis. Meanwhile, lysosome-related gene sets were obtained from the Gene Ontology database.
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