ORIGINAL RESEARCH article Volume 13 - 2025 | https://doi.org/10.3389/fped.2025.1662259 Introduction Chronic kidney disease (CKD) is characterized by a glomerular filtration rate (GFR) below 60 ml/min/1.73 m2 persisting for ≥3 months or the presence of structural or functional kidney damage markers (1). The leading causes of pediatric CKD include congenital anomalies, obstructive uropathies, and hereditary nephropathies, which often present asymptomatically during early stages (2).