Keywords Alzheimer's disease hippocampus place cells stability replay memory electrophysiology behavior Introduction The hippocampus plays a central role in memory for places and events, spatial navigation, and systems-level memory consolidation.1,2,3,4 A key functional basis of the hippocampal role in navigation and spatial memory is the stable, spatially selective activity of place cells, primarily found in hippocampal regions CA3 and CA1.5,6 The population activity of these cells is...