Derek Abbott
Adelaide
Professor at the University of Adelaide
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Articles by Derek Abbott
Self-gating stochastic-resonance-based autoencoder for unsupervised learning
Incorporating additive noise components to an ensemble of McCulloch-Pitts neurons can enhance the information representation of the input, asymptotically approaching the average firing probability for large enough ensembles. We further multiply the input by the average firing probability to control the higher probability of self-gating, thereby forming a unified noise-boosted activation model with learnable noise-related hyperparameters.
Post-translational control of NLRP3 inflammasome signaling
Abstract Inflammasomes serve as critical sensors for disruptions to cellular homeostasis, with inflammasome assembly leading to inflammatory caspase activation, gasdermin cleavage, and cytokine release. While the canonical pathways leading to priming, assembly, and pyroptosis are well characterized, recent work has begun to focus on the role of post-translational modifications (PTMs) in regulating inflammasome activity.
Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies
Current Issue There are no results at this time LATEST NEWS PANX1 pulls the trigger on pyroptosis In response to chemotherapy, the induction of apoptotic cell death can be converted to a form of lytic cell death called pyroptosis through the pore-forming protein gasdermin E, which can trigger an antitumor immune response. Zhou et al. uncovered alternate pathways to chemotherapy-induced pyroptosis.
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
Highlights • Inflammasome activation in the absence of gasdermin D activates gasdermin E • Gasdermin E permits IL-1β release independent of cell death in a sublytic phase • Lysis depends on substantial gasdermin E oligomerization and pore formation Summary Cellular inflammasome activation causes caspase-1 cleavage of the pore-forming protein gasdermin D (GSDMD) with subsequent pyroptotic cell death and cytokine release.
Study of vibrational resonance in nonlinear signal processing
1. Introduction Vibrational resonance (VR), firstly reported by Landa & McClintock [1], describes the resonant behaviour of the response of a bistable model to a low-frequency signal by optimizing the amplitude of a high-frequency periodic vibration.
Terahertz optical fibers [Invited]
M. S. Islam, J. Sultana, M. Biabanifard, M. J. Nine, Z. Vafapour, C. M. B. Cordeiro, A. Dinovitser, B. W.-H. Ng, and D. Abbott, “Tunable localized surface plasmon graphene metasurface for multiband superabsorption and terahertz sensing,” Carbon 158, 559–567 (2020). [Crossref] S. Yang, X. Sheng, G. Zhao, S. Lou, and J. Guo, “Anti-deformation low loss double pentagon nested terahertz hollow core fiber,” Opt. Fiber Technol. 56, 102199 (2020). [Crossref] Y.-F. Zhu, M.-Y. Chen, and Y.
Publisher Correction: Truels and strategies for survival
Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-45253-5, published online 20 June 2019 The original version of this Article contained errors in the figures. The correct Figure 2 was missing, and Figures 3 and 4 were incorrectly given as Figures 2 and 3 respectively. The figures have now been corrected in the PDF and HTML versions of the paper.
The use of photoplethysmography for assessing hypertension
Abstract The measurement of blood pressure (BP) is critical to the treatment and management of many medical conditions. High blood pressure is associated with many chronic disease conditions, and is a major source of mortality and morbidity around the world. For outpatient care as well as general health monitoring, there is great interest in being able to accurately and frequently measure BP outside of a clinical setting, using mobile or wearable devices.
Localized surface plasmon resonance biosensor: an improved technique for SERS response intensification
Md. Saiful Islam, Jakeya Sultana, Rifat Ahmmed Aoni, Md. Selim Habib, Alex Dinovitser, Brian W.-H. Ng, and Derek Abbott Author Affiliations Md. Saiful Islam,1,2,* Jakeya Sultana,1 Rifat Ahmmed Aoni,3 Md. Selim Habib,4 Alex Dinovitser,1 Brian W.-H.
A battery-less and wireless wearable sensor system for identifying bed and chair exits in a pilot trial in hospitalized older people
Falls in hospitals are common, therefore strategies to minimize the impact of these events in older patients and needs to be examined. In this pilot study, we investigate a movement monitoring sensor system for identifying bed and chair exits using a wireless wearable sensor worn by hospitalized older patients. We developed a movement monitoring sensor system that recognizes bed and chair exits.
Identification of The Somerton Man
An unidentified man was found dead on Somerton Beach, Adelaide, Australia, on 1st December 1948. He was physically fit, wearing a smart suit and tie. He had no ID and the labels were removed from his clothes. There were no signs of violence, and to this day we don't know who he is or how he died. Intriguingly, a slip of paper was found in one of his pockets with the printed words "Tamám Shud," meaning "ended" or "finished" in Persian. It was from the book of poetry The Rubáiyát of Omar Khayyam.
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