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Enhanced Dendritic Compartmentalization in Human Cortical Neurons
(A–F) Somatic properties of L5 neurons (rat: n = 70 recordings from 18 rats; human: n = 39 recordings from 6 patients). (E) Percentage of cells exhibiting bursts with cut-off frequencies at 100, 150 or 200 Hz. (F) Percentage of cells exhibiting bursts with 2, 3, 4, or more than 4 APs above 100 Hz. (G) Resting membrane potential as a function of distance from the soma (rat: n = 88 recordings from 22 rats; human: n = 42 recordings from 7 patients).
Genome-scale investigation of olfactory system spatial heterogeneity
The early olfactory system is organized in parallel, with numerous, specialized subsystems established by the modular and topographic projections of sensory inputs. While these anatomical sub-systems are in many cases demarcated by well-known marker genes, we stand to learn considerably more about their possible functional specializations from comprehensive, genome-scale descriptions of their molecular anatomy.
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