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dhruvin patel

As seen in: Nature, Wiley Online Library, BioRxiv, Optometry Today, People Management, Enterprise Nation

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dhruvin patel’s Journalist Portfolio

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Articles

STING is a key driver of Japanese encephalitis virus induced inflammatory response

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By Simran Chhabra, dhruvin patel, Kiran Sharma, Vishal Sah, Santosh Chauhan, Manjula Kalia, Krishnan H. Harshan
| Nature Verified
Abstract Interferon (IFN) and inflammation are the key early defence mechanisms that combat pathogen infection. The cytosolic DNA sensor cGAS activates immune signaling via the stimulator of interferon genes (STING) protein. Emerging evidence suggests crosstalk between innate immune DNA and RNA sensing, implicating a role of STING protein in RNA virus infection. This study characterizes STING in the context of Japanese encephalitis virus (JEV), an RNA virus of the flaviviridae family.
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A Clinical Prediction Model for Inadequate Hemoglobin Response After Red Blood Cell Transfusion

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By dhruvin patel, Rudraksh Kesharwani, Ritika Agarkar
| Wiley Online Library Verified
1 Introduction Red blood cell (RBC) transfusion remains one of the most frequently performed therapeutic interventions in hospitalized patients and plays a central role in the management of anemia and acute blood loss. Contemporary transfusion practice is guided by restrictive transfusion strategies, with most clinical guidelines recommending transfusion when hemoglobin levels fall below defined thresholds depending on patient comorbidities and clinical status [1-4].
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STING is a key driver of Japanese encephalitis virus induced inflammatory response

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By dhruvin patel, Kiran Sharma, Vishal Sah, Simran Chhabra
| BioRxiv
Abstract Interferon (IFN) and inflammation are the key early defence mechanisms that combat pathogen infection. The cytosolic DNA sensor cGAS activates immune signaling via the stimulator of interferon genes (STING) protein. Emerging evidence suggests crosstalk between innate immune DNA and RNA sensing, implicating a role of STING protein in RNA virus infection. This study characterizes STING in the context of Japanese encephalitis virus (JEV), an RNA virus of the flaviviridae family.
Open in Who Shared Issue with article?
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