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Diana Shi on Muck Rack

Diana Shi

Verified
New York
As seen in: People Inc., Yahoo Life, Business Insider, Nature, Mashable, New York Daily News, Chicago Tribune, Entrepreneur, Fast Company, VICE, Flipboard and
Words matter | writer and sm person sometimes | hungry for inspo and pizza | voracious eater, reader + 🐕 feeder | @businessinsider @VICE @TeenVogue

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Articles

DHODH is the key target of the KDM4 inhibitor QC6352 in glioblastoma stem cells

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By Jayden R Sterling, George Joun, Matthew Graus, Tian Du, Mani Kuchibhotla, Terrance G. Johns, G. Gregory Neely, Karen Tran, Chloe Shard, Guillermo Gomez, Ashwini Patil, Diana Shi Verified, Julie-Aurore Losman, Jennifer Baker, Matthew Holland, Paul Brennan Verified, Mathias François, Andreas Kraemer, Susanne Mueller, Yuchen Feng, Paul Workman, Lenka Munoz, Jacinda R. Holtsmark, Antoine deWeck, Angus J. Saxton, Zhihe Lei
| Nature Verified
Abstract Histone lysine demethylase 4 (KDM4) enzymes are frequently overexpressed in cancer and are considered to be promising therapeutic targets. QC6352, which is widely used as a best-in-class KDM4 chemical probe, shows potent antitumor activity across cancer models. Using comprehensive chemical biology approaches in glioblastoma models, we demonstrate that the efficacy of QC6352 and that of its clinical analog zavondemstat are independent of KDM4 inhibition.
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Gerencie a sua energia, não o seu tempo

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By Diana Shi Verified
| Fast Company Brazil Verified
A cena é familiar: depois de um dia de reuniões de trabalho, ligações para resolver problemas inesperados e emails na caixa de entrada, finalmente chega a hora de sentar e pensar criativamente em um grande projeto. Mas sua mente ainda está confusa com outras tarefas e, pelo canto do olho, você vê mais um alerta do aplicativo Teams. Ao mesmo tempo, você sabe que, para realizar um trabalho criativo de sucesso, precisa de espaço para respirar e clareza mental para chegar a uma grande ideia.
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Stop managing your time. Instead, manage your energy

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By Diana Shi Verified
| Fast Company Middle East Verified
Elizabeth Grace Saunders, a time management coach, explains how to dive deep into creative thinking: “I recommend having a meeting-free day each week to immerse yourself in focused work. I reply to messages from the previous business day, and then close email and silence notifications so that the rest of the day [is] free for projects.
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