Diane Barber

1 Introduction: Lysosomes and the Functional Significance of an Acidic Compartment Lysosomes were first identified by Christian de Duve in the 1950s through the discovery of latent acid hydrolase activity that suggested a membrane-bound compartment allowing enzyme function under acidic conditions [1].

By Diane Barber, PhD, APRN, ANP-BC, AOCNP®, FAANP, FAAN, ONS 50th Anniversary Committe Member The beginning of a nursing career is often marked by vivid memories of that very first role after graduation. More than 37 years ago, I began mine at a small community hospital, working evening shifts on the medical-surgical unit. My introduction came through my preceptor, Ellen, a seasoned nurse with a decade of experience.

Conflicts of Interest The authors declare no conflicts of interest. References , , , , and . 1989. “Analysis of the Relationship Between Defective Sperm Function and the Generation of Reactive Oxygen Species in Cases of Oligozoospermia.” Journal of Andrology 10, no. 3: 214–220. https://doi.org/10.1002/j.1939-4640.1989.tb00091.x. , , , et al. 2022. “Role of Reactive Oxygen Species in Aging and Age-Related Diseases: A Review.” ACS Applied Bio Materials 5, no. 9: 4028–4054.