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Dorines Rosario on Muck Rack

Dorines Rosario

As seen in: Cell Reports
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Articles

Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease

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By Sunjae Lee, Dorines Rosario, Gholamreza Bidkhori
| Cell Reports Verified
Highlights • Microbiome functional analysis reveals changes in carbohydrate-active enzymes in PD • Higher number of bacterial mucin and host degradation enzymes link to PD • Metabolic modeling reveals the contribution of bacterial-specific metabolism in PD • Gut-community modeling reveals the role of bacterial folate and homocysteine in PD Summary Parkinson’s disease (PD) is the most common progressive neurological disorder compromising motor functions.
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