Douglas Long

ResearchMetabolismMuscle biology Open Access | 10.1172/jci.insight.182589 JCI Insight. https://doi.org/10.1172/jci.insight.182589. Copyright © 2024, Burke et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Extracellular vesicles (EVs) have emerged as important mediators of inter-tissue signaling and exercise adaptations.

One morning last May, I was sitting in my kitchen in Page, Arizona, drinking coffee and trying to decide what I wanted to do on my birthday, which was two days away. For starters, I would be a no-show at work, which, of course, everyone should do on their birthday. The other plan that came to mind was riding my mountain bike from Big Water, Utah, to Alstrom Point in Glen Canyon National Recreation Area, a ride whose roundtrip distance would roughly approximate the age I would be turning – 56.

Most of Fort Wayne’s numerous haunted places are said to be frequented by spirits that are decidedly humanoid in aspect: the ghost of one Lt. Philip Ostrander roams the city’s namesake Old Fort; a mysterious woman wearing a white, flowing gown is sometimes seen crossing Main Street Bridge west of Van Buren Street; the restless phantom of a maintenance man prowls the dark backstage of the Embassy Theater. The list goes on.