Duanfang Cai

Abstract Wound management remains a significant clinical challenge due to bacterial infection, oxidative stress, and inflammation. To address these issues, we developed a multifunctional hydrogel, NO-GM/Fle@FD, by combining gelatin methacryloyl (GelMA), Pluronic F127 diacrylate (F127DA), the nitric oxide (NO) donor S-nitrosoglutathione (GSNO), and the antibiotic fleroxacin (Fle).

Conflicts of Interest The authors declare no conflicts of interest. References 1, , and , “Fundamentals of Redox Regulation in Biology,” Nature Reviews Molecular Cell Biology 25, no. 9 (2024): 701–719, https://doi.org/10.1038/s41580-024-00730-2. 2, , , , , and , “Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome,” Annual Review of Psychology 71 (2020): 49–78, https://doi.org/10.1146/annurev-psych-122216-011613.

Background It is reported that reduced physical activity and malnutrition may trigger pneumonia, and the utilisation of the geriatric nutritional risk index (GNRI) upon admission to long-term nursing care can enable the implementation of accurate and timely rehabilitation and nutritional support, which may, in turn, minimise pneumonia incidence. However, to date, there is no reported association between GNRI and pneumonia among stable schizophrenic patients.