Dylan Bowen

Results To study fluid force-dependent migration in confinement, we employed microfluidic devices containing moderately (width [W] × height [H] = 20 × 10 μm2) or tightly (W × H = 10 × 3 μm2) confined collagen I-coated microchannels of constant length (length [L] = 200 μm) (Figure 1A). These microchannels were aligned in a parallel arrangement and positioned between two larger, 2D-like channels that served as reservoirs for cells and culture medium (Figure 1A).

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