Dyumn Dwivedi on Muck Rack

Dyumn Dwivedi

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Articles

iPSC-Derived Polyvalent Vaccines as Ontogenetically Informed Immunogens for Overcoming Immune Refractoriness in Microsatellite-Stable Colorectal Cancer: A New Frontier in Cancer Immunotherapy

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By Abhishek Kumar, Dyumn Dwivedi, Mohamed Rahamathulla, Kesavaperumal Gopalakrishnan
| preprints.org
Submitted: 24 November 2025 You are already at the latest version induced pluripotent stem cell (iPSC) vaccines ; oncofetal tumor-associated antigens (TAAs) ; microsatellite-stable colorectal carcinoma (MSS CRC) ; immunogenic cell death (ICD) and epitope spreading ; tumor microenvironment (TME) reprogramming This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited...
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Neutrophil Plasticity and De Novo DUOX2 Expression in Inflammatory Bowel Disease Pathogenesis: A Review of Single-Cell Transcriptomic Advances and Therapeutic Strategies

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By S.T. Gopukumar, Dyumn Dwivedi, Prabhjot Kaur, S. Muthumareeswari
| preprints.org
Submitted: 01 November 2025 You are already at the latest version Inflammatory bowel disease (IBD) arises from the interplay of genetic susceptibility, microbial dysbiosis, and dysregulated innate immunity, leading to chronic intestinal inflammation. Recent advances in single-cell and spatial multi-omics technologies have redefined neutrophils as highly heterogeneous and transcriptionally plastic cells rather than short-lived effectors.
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Multiscale Predictive Cellular Modeling: Integrating Hypothesis Grammars, Digital Twins, and Multi-Omics for In Silico Oncology and Precision Theranostics[v1] | Preprints.org

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By S.T. Gopukumar, Dyumn Dwivedi, Tanveen Kaur Soni, Praveen Ganesh Natarajan
| preprints.org
Submitted: 01 November 2025 You are already at the latest version Predictive multiscale cellular modeling redefines precision medicine by integrating hypothesis grammars, digital twins, and integrative genomics to forecast tumor–immune dynamics, therapeutic resistance, and cellular plasticity. Hypothesis grammars translate mechanistic theories into executable agent-based models (ABMs) and hybrid ODE–PDE systems, enabling rapid in silico hypothesis testing.
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