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E. Labarta

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Highly-sensitive and homogenous detection of 8-oxoguanine based DNA oxidative damage by a CRISPR-enhanced structure-switching aptamer assay

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By E. Bosch, R.J. Aitken, H.W. Bakos, E. Labarta
| ScienceDirect Verified
Keywords CRISPR-Cas12a Oxidative stress 8-oxoguanine Fluorescent biosensors 1. Introduction Individual genetics, environmental deterioration, and increased life stress contribute to a disruption in the body's balance between reactive oxygen species and antioxidant mechanisms, resulting in abnormal oxidative stress in the organisms (Franci et al., 2022; Saenen et al., 2019; Traina et al., 2022).
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