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E. Magda Barbu on Muck Rack

E. Magda Barbu

As seen in: Cell Press
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Articles

Targeted Phage Display-Based Pulmonary Vaccination in Mice and Non-human Primates

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By Daniela I. Staquicini, E. Magda Barbu
| Cell Press Verified
Highlights Discovery of a new ligand-directed lung delivery system based on in vivo phage display Phage pulmonary delivery is safe and does not interfere with lung homeostasis α3β1 mediates the transport of CAKSMGDIVC-phage to the systemic circulation Pulmonary delivery of CAKSMGDIVC-phage elicits a systemic humoral immune response Context and Significance The alveolar-capillary layer of the lung is an attractive and minimally invasive route for local and systemic immunization.
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