Eilidh Fenner on Muck Rack

Eilidh Fenner

As seen in: Nature, PLOS ONE, medRxiv
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Articles

Analysis of rare coding variants in schizophrenia-associated genes and generalised cognition in the UK Biobank

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By Eilidh Fenner, Peter A Holmans, Michael O’Donovan, Michael Owen, James Walters, Elliott Rees
| Nature Verified
Abstract Cognitive impairments in schizophrenia are associated with poor outcomes and are largely unimproved by current medications. It remains uncertain to what extent cognitive impairments arise from shared aetiology and biology with schizophrenia, or are a consequence of having the condition.
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Genetics to Improve Outcomes in Schizophrenia (GENios): A within-case molecular genetic study protocol

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By Sophie E. Smart, Clinical Neurosciences, Eilidh Fenner, Rhys Humphreys
| PLOS ONE
Citation: Smart SE, Fenner E, Humphreys R, Wells A, Fender K, Bresner C, et al. (2026) Genetics to Improve Outcomes in Schizophrenia (GENios): A within-case molecular genetic study protocol. PLoS One 21(2): e0340584. https://doi.org/10.1371/journal.pone.0340584 Editor: Avanti Dey, Public Library of Science, UNITED STATES OF AMERICA Received: December 12, 2025; Accepted: December 22, 2025; Published: February 5, 2026 Copyright: © 2026 Smart et al.
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The relationship between schizophrenia polygenic scores, blood-based proteins and psychosis diagnosis in the UK Biobank - Schizophrenia

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By Sophie E Legge, Eilidh Fenner, Kimberley M. Kendall
| Nature Verified
Abstract Despite notable progress in psychiatric genomics, there are no validated blood-based biomarkers for psychosis. Previous studies have failed to establish a link between schizophrenia polygenic scores (PGS) and blood protein levels. We aimed to identify associations between schizophrenia PGS and blood-based proteins, and to determine whether levels of 2077 proteins differ in individuals with psychosis. We analysed proteomic and genomic data from 47,969 participants in the UK Biobank.
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