Elingarami Sauli

Submitted: 31 December 2024 You are already at the latest version African herbal medicine has been used for centuries as a means of treating various ailments. However, limitations in the effectiveness and delivery of these herbal remedies have necessitated exploration of alternative approaches to enhance their efficacy. Nanotechnology offers promising solutions by providing novel methods for delivery, targeting, and controlled release of bioactive compounds from the herbal medicines.

Keywords Tuberculosis Inflammation Glutathione N-acetylcysteine TB-Biomarkers Introduction Tuberculosis (TB) has remained a major global health concern despite concerted efforts toward its elimination.1 Recent studies have confirmed that a substantial burden of cardiorespiratory illness persists despite ostensibly successful tuberculosis treatment.2–4 Adjunctive host-directed therapeutics (HDTs) have been proposed to address this unmet need.5 One such candidate, N-acetylcysteine (NAC), has...

1. Introduction Tuberculosis (TB) is a global public health problem responsible for high mortality worldwide until the recent COVID-19 pandemic [1]. The World Health Organization (WHO) reported a total of 10.6 million TB cases and 1.6 million deaths in 2021, of whom 0.2 million occurred in people living with human immunodeficiency virus (PLHIV) [1]. Better TB diagnostic and monitoring tools are urgently needed for the detection of TB and clinical management of patients on TB therapy.