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Impact of Common Vitamin D-Binding Protein Isoforms on Supplemental Vitamin D3 and/or Calcium Effects on Colorectal Adenoma Recurrence Risk: A Secondary Analysis of a Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA Oncology | JAMA
Key Points Question Do functional missense variants encoding common vitamin D–binding protein (DBP) isoforms (DBP1s, DBP1f, and DBP2) modify vitamin D3 and/or calcium supplementation effects on colorectal adenoma recurrence risk? Findings In this secondary analysis of a randomized clinical trial that included 1604 patients, the presence of the DBP2-encoding GC rs4588*A allele modified the effects of vitamin D3 and/or calcium supplementation on adenoma recurrence.
Circulating Sex Hormones and Risk of Colorectal Adenomas and Serrated Lesions in Men
Null Results in Brief Jane C. Figueiredo, Gillian Gresham, Elizabeth L. Barry, Leila A. Mott, Michael N. Passarelli, Patrick T. Bradshaw, Carlton W. Anderson and John A. Baron DOI: 10.1158/1055-9965.EPI-21-0713 Published January 2022 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.
Circulating Sex Hormones and Risk of Colorectal Adenomas and Serrated Lesions in Men
Null Results in Brief Jane C Figueiredo, Gillian Gresham, Elizabeth L Barry, Leila A Mott, Michael N Passarelli, Patrick T Bradshaw, Carlton W Anderson and John A Baron DOI: 10.1158/1055-9965.EPI-21-0713 Abstract Background: Sex hormones have been implicated in the etiology of colorectal neoplasia in women for over 40 years, but there has been very little investigation of the role of these hormones in men.
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Elizabeth
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