Else-Marit Inderberg on Muck Rack

Else-Marit Inderberg

As seen in: JoVE- Journal of Visualized Experiments
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A Spheroid Killing Assay by CAR T Cells

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By Pierre Dillard, Else-Marit Inderberg
| JoVE- Journal of Visualized Experiments
Adoptive cell transfer (ACT) represents the next generation cancer treatment. It relies on the injection of effector cells (T- or NK-cells) into a patient. These cells can be genetically modified with a receptor that will guide them to their target, the tumor, and destroy it. Recently this approach was shown to be feasible when a Chimeric Antigen Receptor (CAR) directed against the B-cell marker CD19 was introduced into the patient T cells to kill his/her cancer1.
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