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Modified FOLFIRINOX Versus CISGEM Chemotherapy for Patients With Advanced Biliary Tract Cancer (PRODIGE 38 AMEBICA): A Randomized Phase II Study
Abstract Whether triplet chemotherapy is superior to doublet chemotherapy in advanced biliary tract cancer (BTC) is unknown. In this open-label, randomized phase II-III study, patients with locally advanced or metastatic BTC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were randomly assigned (1:1) to receive oxaliplatin, irinotecan, and infusional fluorouracil (mFOLFIRINOX), or cisplatin and gemcitabine (CISGEM) for a maximum of 6 months.
Everolimus after hepatic arterial embolisation therapy of metastases from gastrointestinal neuroendocrine tumours: The FFCD 1104-EVACEL-GTE phase II study
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig. 1 Kaplan–Meier analysis of hepatic progression-free survival (hPFS), progression-free survival (PFS) (a) and overall survival (b) are presented as well as and percentage change from baseline according to RECIST criteria (c). S, stable disease; P, progressive disease; RP, partial response; RC, complete response.
14 Signs You Could Be Having a Panic Attack
A panic attack is not the hand-wringing worry we all have once in a while. It’s more like an anxiety bomb. It’s swift and powerful, and it can strike out of the blue. Panic attacks activate the body’s fight-or-flight response, causing a cacophony of unpleasant psychological and physical sensations, especially extreme fear or discomfort. You might feel like you’re losing your mind or you’re on death’s door.
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