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Emily Lee on Muck Rack

Emily Lee

New York
As seen in: Medium, Nature, Wiley Online Library, Food Network, MDPI, Substack, Yahoo, Business Report, Oprah Winfrey Network (OWN), Oprah's Super Soul and
❤️5•13•14❤️ Proctor Phantom - Rockclimber I may not do sports but I climb and we consider it one!
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Articles

Microglia integrated neural spheroids enable neuroinflammatory responses and correct network dysfunction induced by alpha-synuclein mutation

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By Jiajing Zhang, Yi Wei Lim, Angelica Medina, Yu-Chi Chen, Yining Wang, Martín Carvajal, Marc Ferrer, Emily Lee
| Nature Verified
Abstract Microglia are the primary resident immune cells of the brain, playing both protective and deleterious roles in neurological diseases, which makes them an enticing therapeutic target. Here we developed a Neural Microglia Integrated Multicellular iPSC-derived Cultured Spheroids (NeuroMIMICS) system that enables measurements of both neural network activity and immune responses using human iPSC-derived microglia, astrocytes, and neurons.
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Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities

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By Itziar Uriarte-Arrazola, Míriam Magallón-Lorenz, Juana Fernández-Rodríguez, Jiajing Zhang, Emily Lee, Kelli M. Wilson, Ignacio Blanco Verified, Hèctor Salvador, Cleofé Romagosa, Conxi Lázaro, Helena Mazuelas, Bernat Gel, Marc Ferrer, Meritxell Carrió, Eduard Serra, Sara Ortega-Bertran, Edgar Creus-Bachiller, Judit Farrés-Casas, Crystal McKnight, Katlin Recabo
| Nature Verified
Abstract Neurofibromatosis Type 1 (NF1) predisposes to peripheral nerve tumor development. The progression from a benign plexiform neurofibroma (PNF) towards a deadly malignant peripheral nerve sheath tumor (MPNST) is not completely understood but commonly involves the sequential loss of NF1, CDKN2A, and polycomb repressive complex 2 (PRC2). Here we use an iPSC-derived neural crest (NC) model to reproduce this malignant transformation through gene editing.
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How Does Discord Make Money?

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By Emily Lee
| 9meters
Discord is a popular communication platform loved by millions of users worldwide, especially gamers. While the basic service is free, many people wonder how the company stays afloat financially. Discord makes money primarily through its Nitro subscription service, server boosts, and partnerships with game developers where they take a 10% cut of games sold through their platform. Unlike many tech companies, Discord didn’t start out profitable.
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