Emily Meredith

Abstract Transmembrane CD13 assembles protein complexes at the plasma membrane to enable diverse cellular processes such as cell-cell adhesion, focal adhesion turnover, endocytosis and recycling of cell surface proteins. In this study, we demonstrate a novel CD13-dependent assembly platform that regulates phosphoinositide (PI) signal transduction during the formation of Tunneling Nanotubes (TNTs).

Open AccessArticle by Emily M. Meredith 1,†, Lauren T. Harven 1,† and Andrew D. Berti 1,2,* 1 Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA 2 Department of Biochemistry, Microbiology and Immunology, College of Medicine, Wayne State University, Detroit, MI 48201, USA * Author to whom correspondence should be addressed. † These authors contributed equally to this work.

Charan Kumar V. Devarakonda, Emily Meredith, Mallika Ghosh and Linda H. Shapiro J Immunol March 1, 2021, 206 (5) 923-929; DOI: https://doi.org/10.4049/jimmunol.2001062 Abstract The Coronaviridae family includes the seven known human coronaviruses (CoV) that cause mild to moderate respiratory infections (HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU1) as well as severe illness and death (MERS-CoV, SARS-CoV, SARS-CoV-2).