Emmet McCormack on Muck Rack

Emmet McCormack

As seen in: Cell Reports Medicine
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Articles

Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors

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By Rafaela Abrantes, Christopher Forcados, David Warren, Liliana Santos-Ferreira, Ana Filipa Costa, Rui Henrique, Puneet Rawat, Pascal F Gelebart, Emmet McCormack, Line Bjørge, Ben Davidson , Victor Greiff, Daniela Elena Costea, Filipe Pinto, Kjersti Flatmark, Catarina Gomes, Else Marit Inderberg, Celso A. Reis, Karianne Giller Fleten, Emanuel Senra, Klara Krpina, Ann Magritt Liberg, Sébastien Wälchli
| Cell Reports Medicine
Keywords immunotherapy CAR T cells glycosylation sialyl-Tn cancer antibodies glycobiology solid tumors Introduction Chimeric antigen receptor (CAR) T cell therapy has garnered significant attention for its remarkable clinical success in the treatment of hematological malignancies.1,2,3 However, the successful translation of CAR T cell immunotherapy to treat solid tumors remains a difficult task.4,5,6,7 Aside from the challenging accessibility of certain anatomical regions and the presence of...
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