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Enolia Marr on Muck Rack

Enolia Marr

As seen in: Cell Host & Microbe
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Articles

RNA quality control enables antibiotic tolerance

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By Andrew T. Nishimoto, Michelle R. Scribner, Yanying Yu, Qidong Jia, Haley Echlin, Amy Iverson Verified, Abigail McKnight, Nadia B. Olivero, Aaron Poole, Adam Rosenthal, Chrispin Chaguza, Randolph K. Larsen, Mark E. Hatley, Ralph R. Isberg, Vaughn S Cooper, Tim van Opijnen, Jason Rosch, Juan C. Ortiz-Marquez, Enolia Marr, Jordan Coggins
| Cell Host & Microbe Verified
Results To evaluate how antibiotic treatment and host immune condition interact to constrain or drive pathogen adaptation, we propagated S. pneumoniae populations of TIGR4, a virulent serotype 4 pneumococcal strain, in mice across three distinct immune states: immunocompetent, neutrophil-depleted, and macrophage-depleted (Figure 1A).
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