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Ensi Ma

As seen in: Nature, Cell Press
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Articles

Targeting cholesterol esterification sensitizes liver cancer to CD8 + T cell attack by impairing metabolic and redox resilience

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By Yange Gu, Lulu Zhang, Jianhua Li, Ensi Ma, Weiwei Hu, Yun Liu, Xiaocheng Du, Feifei Zhang, Wenfeng Li, Yitian Jin, Yinghua Wang, Zihan Ning, Chune Yu, Jing Zhao, Chenqi Xu, Zhengxin Wang, Guangchuan Wang, Linyue Bian
| Cell Press Verified
Keywords immunotherapy cholesterol metabolism SOAT1 hepatocellular carcinoma CAR-T cell therapy anti-PD-1 immune evasion lipid metabolism tumor recurrence oxidative stress Get full text access Log in, subscribe or purchase for full access. References 1. Llovet, J.M. ∙ Kelley, R.K. ∙ Villanueva, A. ... Hepatocellular carcinoma Nat. Rev. Dis. Primers. 2021; 7, 6 2. Marsh, J.W. ∙ Dvorchik, I. ∙ Subotin, M. ...
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EBNA1BP2 (EBP2) promotes the progression of hepatocellular carcinoma through upregulating the expression of MCM8 and HMGB1

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By Hao Xing, Chao Sun, Yangyang Zhan, Jianhua Li, Hongyuan Xue, Ruidong Li, Yifeng Tao, Ensi Ma, Quanbao Zhang, Conghuan Shen
| Nature Verified
Abstract Primary liver cancer ranks among the most prevalent and refractory malignant tumors globally. This investigation delves into the role of Epstein-Barr virus nuclear antigen 2-binding protein (EBP2) in hepatocellular carcinoma (HCC). Significantly, EBP2 exhibits marked overexpression in HCC tissues, a finding that correlates with advanced tumor staging and unfavorable prognostic outcomes.
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