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Ethan Fan

As seen in: Nature, Wiley Online Library, HMP Global Learning Network
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Articles by Ethan Fan

Caregiver Burden in a Home-Based Primary Care Population: Is Assisted Living a Factor?

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By Matthew Cali, Ethan Fan, Namirah Jamshed
| HMP Global Learning Network
Caregiver burden is an essential component of long-term care not evaluated within assisted living facilities (ALFs). This study assessed caregiver burden among caregivers of older adults enrolled in a home-based primary care program, comparing burden among caregivers of ALF residents vs patients cared for at home. Caregivers completed a survey with the Short Form Zarit Burden Interview (ZBI-12) via the patient portal; 76 of 364 caregivers completed the survey (20% response rate).
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A cough sound-based deep learning algorithm for accessible prompt detection of chronic obstructive pulmonary disease with smartphones

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By Jun L Zhou, Jingwen Huang, Qian Wang, Huifang Cao, Lin Huang, Si Chen, Wenyu Zhu, Jiaxuan Mao, Yang Liu Verified, Zhaoyang Bu, Mo Yang, Yi Zhou, Ethan Fan, Xianwen Sun, Ping Wang, Min Zhou, Jieming Qu, Junhai Yan, Xiaolu Ruan, Leanne Tong, Dongxing Zhao
| Nature Verified
Abstract Early COPD diagnosis is vital for effective management, yet conventional tools such as professional spirometers are often inaccessible in resource-limited settings. We present Cough Search, a smartphone-based deep learning algorithm that uses voluntary cough sounds to detect COPD, offering a cost-efficient and accessible diagnostic approach. The presented COPD detection algorithm (Cough Search) employs a transformer-based neural network model.
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Capivasertib plus fulvestrant in patients with HR-positive/HER2-negative advanced breast cancer: phase 3 CAPItello-291 study extended Chinese cohort - Nature Communications

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By Xichun Hu, Qingyuan Zhang, Tao Lin Sun, Yen-Shen Lu, Xiaojia Wang, Ethan Fan, Shin-Cheh -Chen
| Nature Verified
Abstract In the global CAPItello-291 randomized phase 3 study (NCT04305496) in patients with hormone receptor-positive/HER2-negative advanced breast cancer and progression during/after aromatase inhibitor treatment, capivasertib–fulvestrant significantly improved progression-free survival (PFS) in the overall population and patients with PIK3CA/AKT1/PTEN-altered tumors versus placebo–fulvestrant.
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d‐mannosuria levels measured 1 h after d‐mannose intake can select out favorable responders: A pilot study

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By Ethan Fan, Marjan Dashti, Jorge Luis Fuentes, Larry Reitzer
| Wiley Online Library Verified
Abstract Background d-mannose is used as preventive measure against recurrent urinary tract infections (RUTIs). We studied d-mannosuria after a challenge test to identify favorable responders that could be targeted for long-term preventive therapy.
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