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Tao Lin Sun

As seen in: Color Research & Application, Nature, Wiley Online Library, arXiv, PLOS, PLOS Biology, ScienceDirect, BMJ Open, Educational Studies, Elsevier and
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Articles

First-line PD-1/VEGF bispecific antibody plus chemotherapy in triple-negative breast cancer: a phase 2 trial

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By Xiying Shao, Can Tian, Zhanhong Chen, Jian Huang, Yongsheng Wang, Tao Lin Sun, Tienan Yi, Yifen Wu, Weihua Sun, Zhongmin Wang, Baiyong Li, Yu Xia, Xiaojia Wang, Quchang Ouyang, Xufang Yu
| Nature Verified
Abstract Triple-negative breast cancer is an aggressive subtype comprising 10–20% of all breast cancer cases and has a worse prognosis than other subtypes. This open-label, multicenter, single-arm, phase 2 clinical trial evaluates the safety and efficacy of ivonescimab combined with chemotherapy as first-line treatment in female patients with locally advanced unresectable or metastatic triple-negative breast cancer who have not received previous systemic therapy.
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Computer Science > Computation and Language

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By Yuan Xia, Tao Lin Sun
| arXiv
Reinforcement learning with verifiable rewards has been especially effective in mathematics and coding, where answers can be checked automatically. Many open-ended medical questions lack comparably cheap outcome verifiers: responses may be partly correct, incomplete, or contain clinically consequential errors. Rubrics written or validated by physicians offer strong clinical grounding, but involving experts in every instance is costly.
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Dissecting PROTAB-mediated degradation of cell surface proteins

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By Jieyan He, Tao Lin Sun, Mengwen Zhang
| Wiley Online Library Verified
Conflict of interest All authors are employees of Roche/Genentech, a member of the Roche Group. Data availability statement All data are available upon request. Supporting Information Filename Description febs70670-sup-0001-supinfo.pdfPDF document, 1.4 MB Fig. S1. Checkerboard titration of HER2-LgBiT and ZNRF3-smBiT plasmids A checkerboard titration was performed using HER2-LgBiT and ZNRF3-smBiT plasmids, with a 3-fold dilution starting from 30 ng.
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