Fabian Weiss

Abstract Adenoviral vectors demonstrate encouraging clinical outcomes for B- and T-cell vaccines. With such approaches, multiple payloads can be delivered, beyond the antigen itself. Nevertheless, the human adenoviral vector serotype C5 (HAdV5) exhibits limited transduction efficiency to dendritic cells (DC), therefore necessitating very high viral loads. Targeting antigen-presenting cells (APC) has remained challenging.

If you were to triangulate where the Fonz is most popular in the modern era, there’s a good chance that Scandinavia would be a hardcore Happy Days hot spot. The squeaky-clean American era of rock ‘n’ roll music, muscle cars and pinup style is considered a golden age by a group of young and old Swedes, whose backyards are crammed with classic cars like Pontiacs, Mustangs and Buicks. Pompadour haircuts and polka-dotted skirts are part of everyday life for the Swedish Raggare.

A four-hour ferry ride off the coast of Estonia, the sunlit conifers and coastal meadows of Kihnu Island rise gently from the Baltic Sea. You can bike from one end to the other in half an hour. Its four villages house around 700 people—only two thirds of whom live there year-round—and there is no hotel. Yet the island receives 12 times more tourists per resident than some of the most visited places in the world. These tens of thousands of visitors don’t come for landmarks or amusement parks.