Fabiola Susanna Emser on Muck Rack

Fabiola Susanna Emser

As seen in: The Journal of Biological Chemistry
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Articles

Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor

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By Nataša Tomašević, Fabiola Susanna Emser, Edin Muratspahić, Jasmin Gattringer
| The Journal of Biological Chemistry
ABSTRACT The cannabinoid-type 2 receptor (CB2R), a G protein-coupled receptor (GPCR), is an important regulator of immune cell function and a promising target to treat chronic inflammation and fibrosis. While CB2R is typically targeted by small molecules, including endo-, phyto- and synthetic cannabinoids, peptides – owing to their size – may offer a different interaction space to facilitate differential interactions with the receptor.
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