Faranaz Atschekzei

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis of multiple joints, and the peak age of onset has been reported to be in the 30s in the 1950s [1]. However, recent studies showed that the peak age of RA onset is increasing [[2], [3], [4]]. A Japanese study also indicated that the peak RA onset during 2012–2013 was in the 60s [5].

Discussion Rheumatic manifestations and especially arthritis have been variably reported as autoimmune manifestations of PADs.12 14 28 In the present retrospective study, in a cohort of patients with PAD, the prevalence of inflammatory arthritis amounted to approximately 16%, which is higher than previously reported.9–12 The latter might be explained through selection bias, due to the fact that our outpatient clinic is a tertiary referral centre both for rheumatic disorders and primary...

Detection of variants in genes associated with autoinflammatory disorders in patients with PsA The employed targeted NGS approach included all genes, which were associated with IEI, classified as autoinflammatory disorders (group VII of the International Union of Immunological Societies (IUIS) classification of IEI) as well as genes associated with disorders from alternative groups, that have also been associated with autoinflammatory manifestations.20 Considering AF as well as measures of...