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Fatemeharefeh Nami on Muck Rack

Fatemeharefeh Nami

As seen in: Mary Ann Liebert, Inc.
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Articles

Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing

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By Fatemeharefeh Nami, Roya Ramezankhani, Marjan Vandenabeele, Tim Vervliet
| Mary Ann Liebert, Inc.
Introduction In vitro human disease modeling has become possible because of the development of induced pluripotent stem cells (iPSCs), allowing study of disease pathogenesis and drug screening for otherwise inaccessible human cells.1,2 One of the important obstacles in iPSC technology is the variability between different lines caused by donor differences, reprogramming methods, and genetic background.3 Therefore, it is crucial to create isogenic iPSCs that differ from the patient iPSCs only...
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