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Fehim Esen on Muck Rack

Fehim Esen

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Articles

Effect of Transdermal Estrogen Therapy on Bone and Neurobehavioral Health in Youth with Premature Ovarian Insufficiency: A Case-Control Study

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By Khashayar Sakhaee, Alireza Zomorodian, Mustafa Hepokur, Fehim Esen
| ScienceDirect Verified
Premature ovarian insufficiency (POI) during adolescence is rare, affecting less than 1 in 10,000 individuals,1,2 and is frequently associated with underlying genetic conditions or previous exposure to chemotherapy. In these situations, estrogen deficiency can be anticipated and replacement initiated before consequences on bone health arise. Conversely, the diagnosis of idiopathic POI is often delayed due to the assumption that irregular menses are common among adolescents.
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